Adding a balloon or stent procedure (endovascular angioplasty to widen blood vessels in the neck) to standard treatment may make little to no difference to the chance of another stroke or mini-stroke ...

Current evidence does not allow firm conclusions regarding the safety of treatment with insulin-like growth factor-1, a protein that helps blood vessels in the retina of the eye grow normally, in ...

Choosing to fix the patch with glue or a self-sticking patch compared to using stitches, tacks, or staples may make little to no difference to the risk of long-term pain and the hernia coming back.

In people with stomach cancer, there may be little to no difference in survival and the chance of the cancer coming back whether the spleen is removed or kept during surgery to remove the stomach. We ...

Compared with placebo (dummy treatment), antibiotics may reduce back pain slightly and may have some beneficial effect in improving disability in the short term in people with low back pain linked to ...

Our Handbooks describe the process of preparing and maintaining diverse types of systematic reviews. Handbooks are updated regularly to reflect advances in systematic review methods and in response to ...

This Cochrane Review summarises evidence from 14 randomised controlled studies evaluating the effectiveness and safety of scopolamine for motion sickness. The results show that scopolamine is more ...

Compared to daily oral pre-exposure prophylaxis (PrEP), lenacapavir reduces the number of new HIV infections by many more; causes slightly fewer serious unwanted effects; and results in little to no ...

Newborn resuscitation training (NRT) programmes may decrease newborn deaths in the first 28 days after birth, mainly during the first 24 hours and the first 7 days after birth. Studies are still ...

Immediate skin-to-skin contact between newborns and their mothers offers a better start in life, improving a number of key health metrics, according to a newly-updated Cochrane review. The review ...

Falls by older people in care facilities, such as nursing homes, and hospitals are common events that may cause loss of independence, injuries, and sometimes death as a result of injury. Effective ...

New evidence published in the Cochrane Library today finds MMR, MMRV and MMR+V vaccines are effective and that they are not associated with increased risk of autism. Measles, mumps, rubella and ...